In sales training, no response = no.
I know to the receiver, that it's not always a direct no. However, this one factor, is a defining one, for all successful business owners. It's kind of the same thing too, in all therapeutic change work.
You ask once. You receive a response. You move on. (A non-response is a no, so you move-on.)
Successful Sales Team Members, they are meeting new people, and building relationships. Them focusing on relationships, and "yes"'s, is the defining factor.
There is another tier of sale professionals, who have a different psychology, which is well described in managerial books about sales archetypes. They, are more organized, and their strategy, is keeping in touch, with more people, and following up. Those professionals, usually have less annual sales than the aforementioned type, but, they may have more, over time, with less cancelled contracts. They're successful in relationship building and cultivation. These, are important values and behaviors.
I believe there is one factor, when a no, is not really a no. And that is when the message never get's through. When there is a technical error, or security breach. People don't know what you know, if they never get the message.